terminal differentiation

CONCLUSIONS RI α antisense genes could induce lung cancer cells to terminal differentiation and apoptosis .

结论RIα反义基因片段可诱导人肺癌细胞进入终末分化至编程性细胞死亡。

Investigation on the expression of the terminal differentiation protein in the keratinocyte of senile face and leg skin

老年人面部、小腿皮肤角朊细胞终末分化蛋白的研究

The Effects of Retinoic Acid on the Morphology and Terminal Differentiation of SK-N-SH Cell

维甲酸对人神经母细胞瘤SK-N-SH细胞形态结构和分化标志物表达的影响

But both of them produce similar induction of terminal differentiation of HL-60 cells in NBT assay .

在NBT实验中，这两类因子都产生了类似程度的诱导HL-60细胞向粒细胞方向的终末期分化。

The Effects of Ginsenoside Rg1 on the Morphology and Terminal Differentiation of Human Osteosarcoma MG-63 Cell

人参皂甙Rg1对人成骨肉瘤MG-63细胞形态结构和终末分化指标的影响

Terminal Differentiation of Human Acute Promyelocytic Leukemia ( APL ) Cells Induced by Tanshinone ⅱ A in Primary Culture

丹参酮ⅡA诱导原代培养人急性早幼粒细胞白血病细胞分化

The hs_2 specific binding proteins related to the erythroid terminal differentiation induced by EDDF

EDDF诱导产生与红细胞终末分化相关的HS2特异结合蛋白

Appearance of some novel proteins binding enhancer element of globin gene ( hs_2 ) during erythroid terminal differentiation

红细胞终末分化期出现与珠蛋白基因表达增强子HS2序列特异结合的蛋白质因子

The result of the malignant proliferation is a block in the ability of cancer cells to undergo quiet , terminal differentiation and / or apoptosis .

这种恶性增殖的结果是肿瘤细胞不再进入静止、衰亡和终末分化。

BMP may induce mesenchymal cells to differentiate into chondrocytes , promote the synthesis of extracellular matrix and inhibit the terminal differentiation of chondrocytes .

BMP分子可以诱导间充质细胞分化为软骨细胞，促进合成细胞外基质，抑制软骨细胞的终末分化。

Concomitant with promoting cell growth and proliferation , c - myc inhibits terminal differentiation of most cell types , and sensitizes cells to apoptosis .

普遍认为c-myc可以促细胞的增殖、永生化、转化，抑制细胞分化并介导凋亡，在肿瘤的发生、发展中具有促细胞增殖和凋亡的双相性。

Filaggrin gene is a member of epidermal differentiation complex , and it closely relates to the formation of cell membrane and terminal differentiation of epidermis .

中间丝蛋白基因是表皮分化复合物基因簇的成员之一，与细胞膜形成及表皮终末分化密切相关。

Study on the Terminal Differentiation of Human Osteosarcoma MG-63 Cells Induced by Ginsenoside Rg1 , Cinnamic Acid , Tanshinone ⅱ A and Their Combinations

人参皂甙Rg1、肉桂酸、丹参酮ⅡA及其组合对人成骨肉瘤MG-63细胞终末分化的诱导研究

Erythroid Differentiation Denucleation Factor : a Family of Erythroid Regulators for Mammalian Erythroid Terminal Differentiation / Tumor Suppression and the Cloning of Their Related Genes

红细胞分化去核因子：哺乳类红细胞终末分化/肿瘤抑制的调节因子家族及其相关基因的克隆

Objective To investigate the roles of mouse erythroid differentiation and denucleation factor ( MEDDF ), newly cloned in our laboratory , in erythroid terminal differentiation .

研究小鼠红细胞分化去核分化因子（MEDDF）在红细胞终末分化中的功能。

It has been considered that neurons were in a state of terminal differentiation after postmitosis . Recently , however , many data have suggested that the mature neurons may reentry into the cell cycle .

过去一直认为神经元处于一种有丝分裂后的终末分化状态，但最近有许多资料表明成熟神经元可以重新进入细胞周期。

CONCLUSION : ATRA cannot induce HL 60 to achieve terminal differentiation , but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis .

结论：ATRA并不能诱导HL-60细胞完成终端分化，但是该药可以诱导白血病细胞向成熟方向分化，而且已分化的肿瘤细胞于发生凋亡。

At slug stage , the activity of PKA in KAX-3 cells functions in the form of oscillatory waves , and has a large amplitude at the end of this stage , which could prepare for terminal differentiation .

在蛞蝓体时期，PKA的活性在KAX-3细胞细胞中表现为振荡波，并且在此期的最后阶段，有一个大的振幅，这可能是为了最终的发育做准备。

ATRA treatment induce terminal differentiation and growth arrest of several established human myeloid cell lines in vitro and has also proven to be effective in the clinical treatment of acute promyelocytic leukemia ( APL ) by inducing differentiation and apoptosis of the immature blasts .

在体外一些髓样细胞系中ATRA可以诱导细胞周期阻滞及启动终末分化。并且由于它的这一特性已在临床用于治疗急性早幼粒细胞性白血病，并取得很好的疗效。

Conclusions Cervical carcinoma in situ showed the characteristics of high PI and abnormal differentiation and restraint of terminal differentiation but may be persistently maintain in a relatively stable state and the proliferating potentiality of cancer cells was limited in some degree in a period of considerable length .

结论原位癌细胞增生活跃，分化异常，终末分化受抑，但在相当长时期内处于相对稳定的状态，即使当大片癌细胞脱落，增生修复时仍然维持原位癌的状态。

In addition , TGF - β and BMP can coordinate with IHH-PTHrP relaying pathway to regulate the differentiation of chondrocytes , and BMP antagonizes with FGF in controlling the chondrocyte proliferation , IHH expression and terminal differentiation of chondrocytes .

另外，TGFβ、BMP分子可以和IHHPTHrP信号通路相互作用协调软骨细胞分化，BMP和FGF分子相互拮抗控制软骨细胞增殖、IHH分子表达和软骨细胞的终末分化。

Ski plays multiple roles in a variety of cell types , it can induce both oncogenic transformation and terminal muscle differentiation when expressed at high levels .

Ski在各种细胞类型中发挥着不同的作用。Ski在细胞中的高表达可以诱导原癌细胞癌变和肌肉细胞终末分化。

Transformed cells have escaped normal growth regulatory signals and may be blocked at discrete states of differentiation prior to the stage of terminal cell differentiation and / or apoptosis .

如果正常的生长调节信号紊乱，细胞终末分化及凋亡障碍，就将发生癌变。

IGF-I stimulates differentiation through a myogenin pathway and functions in the regulation of muscle growth , it also stimulates terminal myogenic differentiation by induction of myogenin gene expression .

在骨骼肌生长过程中，IGF-I调节骨骼肌的生长。IGF-I通过诱导肌细胞生成素（MyoG）基因表达而刺激成肌细胞的终末端分化。